Words similar to tag-specific

Example sentences for: tag-specific

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Due to the nature of this line of TCR transgenic mice, only about 10% of splenic CD4 +T cells are Tag-specific.
Mice with transgenes encoding T cell receptors from H-2k-restricted CD4 +and CD8 +T cell clones specific for Tag have been generated [ 28 29 ] . When Rip1-Tag2 was crossed to TCR transgenic mice (TCR1) carrying Tag-specific CD4 +T cells, temporal induction of T cell tolerance to Tag was detected in the pancreatic draining lymph nodes in the double transgenic mice [ 30 ] . The T cell tolerance is manifested in reductions both of idiotypic CD4 +T cell abundance and of the T cell proliferation response to Tag in vitro.
This may be the result of the "bystander" effects induced by the tumor-infiltrating, Tag-specific, CD4 +T cells.
When the Tag-specific fluorescence (all cell cycle phase fractions) measured by flow cytometry was compared to the intensity of Western blot bands measured by densitometry, the two measurements showed an essentially linear relationship (Figure 2B).
Crosses of Rip1-Tag5 mice to transgenic mice that either increased the abundance of anti-Tag CD4 +T cells (TCR1) [ 28 ] or rendered the tumor cells co-stimulatory (Rip-B7-1) [ 31 ] dramatically enhanced the infiltration of premalignant lesions, but not of solid tumors [ 22 ] . Additionally, ex vivo stimulated Tag-specific CD4 +T cells were transferred into Rip1-Tag5.