Words similar to taa-specific
Example sentences for: taa-specific
How can you use “taa-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:
Furthermore, it may be possible that low-RE TAA-specific T cells may interfere with elicitation of high-RE T cells, either by direct competition for antigen on APC surface [33,34] or down-modulation of peptide–MHC complexes.
A similar phenomenon may occur in vivo, leading to TAA-specific T cells of low RE depending on the nature of antigen stimulation [20].
While endogenous anti-tumor CD8+ T cell responses may already exist in some cancer patients [2], vaccination with TAA-derived peptides, and in particular heteroclitic peptide analogs, increases the frequency of TAA-specific T cell responses to detectable levels in many patients [3,4,5,6,7,8,9].
Diverse TAA-specific T cell responses were found in the four vaccinated patients, with multiple T cells expressing different TCR VB, while the two endogenous responses were less diverse.
One possibility is that elicited TAA-specific T cells are not optimally functional in vivo [2,18].
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