Example sentences for: taa-specific

How can you use “taa-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • All six TAA-specific populations exhibited robust functional responses ex vivo, as measured by percentage of G2090–2M- and M26-tetramer-positive cells that mobilized CD107 and/or downregulated the CD3 complex upon incubation with T2 cells pulsed with cognate peptides (Table 1; 86%-99.

  • To address the complexity of T cell responses against melanoma in vivo, patients with vaccine-induced or endogenous TAA-specific responses were selected.

  • Thus, naïve TAA-specific T cells, with inadequate RE to become activated by low densities of native peptides present on tumor cells, may become efficient in tumor lysis upon vaccination with heteroclitic peptide.

  • While endogenous anti-tumor CD8+ T cell responses may already exist in some cancer patients [2], vaccination with TAA-derived peptides, and in particular heteroclitic peptide analogs, increases the frequency of TAA-specific T cell responses to detectable levels in many patients [3,4,5,6,7,8,9].

  • Similar to the first four vaccine-elicited patients, these four additional patients (six TAA-specific responses in total) exhibited variable reactivity to melanoma targets, ranging from 13% to 49.


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