Words similar to taa-specific
Example sentences for: taa-specific
How can you use “taa-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:
In response to melanoma targets mel526 and Malme-3M, which both express gp100 and MART-1 and are HLA-A*0201 positive, the two endogenous TAA-specific responses (samples from patients 132 and 461) also exhibited robust functional responses directly ex vivo (Table 1; 36.
However, the presence of TAA-specific T cells elicited by vaccination often does not correlate with clinical responses [3,14,15,16,17].
Diverse TAA-specific T cell responses were found in the four vaccinated patients, with multiple T cells expressing different TCR VB, while the two endogenous responses were less diverse.
A similar phenomenon may occur in vivo, leading to TAA-specific T cells of low RE depending on the nature of antigen stimulation [20].
While endogenous anti-tumor CD8+ T cell responses may already exist in some cancer patients [2], vaccination with TAA-derived peptides, and in particular heteroclitic peptide analogs, increases the frequency of TAA-specific T cell responses to detectable levels in many patients [3,4,5,6,7,8,9].