Example sentences for: taa-specific

How can you use “taa-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These data demonstrate that all six TAA-specific CD8+ T cell responses were functional ex vivo, but there were significant differences in reactivity to melanoma targets between endogenous and vaccine-elicited responses.

  • We estimated the composite RE of the overall TAA-specific response (composed of a heterogeneous population of T cells) in vivo by summing the RE of each clone multiplied by its representation in the original mixture (the representation was estimated based on the proportion of TAA-specific cells expressing the same VB as the clone).

  • Thus, naïve TAA-specific T cells, with inadequate RE to become activated by low densities of native peptides present on tumor cells, may become efficient in tumor lysis upon vaccination with heteroclitic peptide.

  • These findings suggest that TAA-specific T cells elicited by heteroclitic peptide vaccination have different tumor-cytolytic potentials from those which develop endogenously to cancer.

  • To determine the effectiveness of tumor lysis by the different TAA-specific T cell clones that were propagated, clones were analyzed for their ability to lyse melanoma cell lines mel526 and Malme-3M.


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