Example sentences for: taa-specific

How can you use “taa-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To address the complexity of T cell responses against melanoma in vivo, patients with vaccine-induced or endogenous TAA-specific responses were selected.

  • However, the presence of TAA-specific T cells elicited by vaccination often does not correlate with clinical responses [3,14,15,16,17].

  • While endogenous anti-tumor CD8+ T cell responses may already exist in some cancer patients [2], vaccination with TAA-derived peptides, and in particular heteroclitic peptide analogs, increases the frequency of TAA-specific T cell responses to detectable levels in many patients [3,4,5,6,7,8,9].

  • We estimated the composite RE of the overall TAA-specific response (composed of a heterogeneous population of T cells) in vivo by summing the RE of each clone multiplied by its representation in the original mixture (the representation was estimated based on the proportion of TAA-specific cells expressing the same VB as the clone).

  • In addition, TAA-specific T cell responses could be detected in some patients without vaccination, suggesting the existence of an endogenous anti-tumor T cell response in these patients.


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