Example sentences for: systemically

How can you use “systemically” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • IL-4 and IL-10 expression in sera of CIA mice administered Ad-mIL-4 systemically

  • Yet, some selective δ ligands have been shown to be ineffective antinociceptive agents when given systemically [ 14 15 16 ] . The reason for this ineffectiveness is not clear.

  • Conversely, IL-10 gene-knockout mice develop a chronic colitis that is extremely similar to IBD [ 25 ] . IL-10 treatment can reduce inflammation in several models of colitis [ 26 27 28 29 30 ] and human IBD [ 31 32 33 34 35 ] . However, the clinical efficacy of systemically administered IL-10 for patients mild to moderately active Crohn's disease has not been as effective as hoped [ 33 34 35 ] . Furthermore the efficacy of IL-10 administration in mouse colitis models is contentious [ 36 ] .

  • We also verified the presence of systemically administered simvastatin in the mouse serum, as this has previously not been reported and is likely to be of critical importance when evaluating the effect of simvastatin on bone.

  • The administration of recombinant IL-4 protein systemically has been shown to be therapeutic in murine CIA models if given before disease onset.


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