Words similar to synaptojanin

Example sentences for: synaptojanin

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Although DNase 1 has only 18% overall sequence identity and the IPP domain of synaptojanin, 14%, to APE1, we could show that most of the areas of identity were in molegos common to all three proteins.
This core is also common to DNase 1 and synaptojanin(an IPP family member), which share the functions of metal ion based cleavage of a phosphate backbone.
If the local alignment with synaptojanin is gapped to align these residues in the three proteins (Table 2, gapped), the RMSD for the two sections separated by the gap is much lower than that if one tries to align the whole ungapped segment.
The first two β-strand molegos in synaptojanin are 2 residues longer than in APE or DNase 1. By regarding these elements as simple lego style blocks, and recognizing the connectivity, molego based alignment correctly defined the changing length of the secondary structure elements.
However, matching these conserved residues between synaptojanin and DNase1 or APE requires a gapping that would not be consistent with CLUSTALW or a structural (DALI [ 35 ] ) alignment of these proteins (Table 2).