Example sentences for: syk

How can you use “syk” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, although these cells carry a highly active Syk kinase, no evidence for downstream signaling was found.

  • found that transfection of a mutant Syk expression construct carrying only the 3F alteration into a T cell lines could overcome the need for TCR occupancy for IL-2 expression in PMA-treated cells [ 62 ] . However, since the mutant Syk used retained kinase activity, these studies could not distinguish between a gain-of-function effect versus a dominant-positive effect as found here.

  • Constitutive Syk activity is insufficient for downstream signaling

  • Site-specific mutations were placed in two regions of Syk.

  • Thus, it appeared that introduction of this mutant form of Syk resulted in a dominant positive effect on kinase activity rather than a dominant negative effect.


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