Words similar to syk
Example sentences for: syk
How can you use “syk” in a sentence? Here are some example sentences to help you improve your vocabulary:
Transfectants were selected in RPMI supplemented with L-glutamine, β-mercaptoethanol and hygromycin B. Bulk culture syk -negative DT40 transfectants were used in the specified experiments.
The second novel observation, that Syk kinase enzymatic activity was insufficient for signal transduction, suggests that multiple biochemical processes may be required for the Syk-dependent step of signal transduction.
In some experiments, rabbit anti-mouse IgM was added to control cells during the lysis step; under these conditions no stimulation of Syk phosphorylation or kinase activity was observed.
found that transfection of a mutant Syk expression construct carrying only the 3F alteration into a T cell lines could overcome the need for TCR occupancy for IL-2 expression in PMA-treated cells [ 62 ] . However, since the mutant Syk used retained kinase activity, these studies could not distinguish between a gain-of-function effect versus a dominant-positive effect as found here.
Syk from all clones analyzed became tyrosine phosphorylated after BCR stimulation (lanes 2, 5, 8 and 11).