Example sentences for: syk

How can you use “syk” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Transfectants were selected in RPMI supplemented with L-glutamine, β-mercaptoethanol and hygromycin B. Bulk culture syk -negative DT40 transfectants were used in the specified experiments.

  • The second novel observation, that Syk kinase enzymatic activity was insufficient for signal transduction, suggests that multiple biochemical processes may be required for the Syk-dependent step of signal transduction.

  • In some experiments, rabbit anti-mouse IgM was added to control cells during the lysis step; under these conditions no stimulation of Syk phosphorylation or kinase activity was observed.

  • found that transfection of a mutant Syk expression construct carrying only the 3F alteration into a T cell lines could overcome the need for TCR occupancy for IL-2 expression in PMA-treated cells [ 62 ] . However, since the mutant Syk used retained kinase activity, these studies could not distinguish between a gain-of-function effect versus a dominant-positive effect as found here.

  • Syk from all clones analyzed became tyrosine phosphorylated after BCR stimulation (lanes 2, 5, 8 and 11).


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