Words similar to syk

Example sentences for: syk

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While wildtype human Syk was capable of autophosphorylation (lane 2 upper panel), the (K395A/3F)Syk mutant was not (lanes 3 and 4) demonstrating that this molecule was kinase-dead.
Constitutive Syk activity is insufficient for downstream signaling
Although activated endogenous Syk was the likely source of the constitutive Syk activity observed in clones that expressed the (K395A/3F)Syk molecule, the possibility remained that the activity might originate from the (K395A/3F)Syk molecule itself.
This is not surprising since the ITAMs in CD79, which are proposed to be docking sites for Syk, are unlikely to be phosphorylated in the absence of BCR stimulation since phosphorylation of these residues likely requires activation of Src family tyrosine kinases expressed in B cells.
This is consistent with the idea that Lyn and Syk are upstream of Btk activation [ 28].