Words similar to swirm
Example sentences for: swirm
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However, a direct comparison showed no specific relationship between the sequence conservation pattern of the SWIRM domain and those of other α-helical bundles that are commonly encountered in chromosomal proteins such as the bromodomain [ 16], the Myb or SANT domains and other helical DNA-binding domains [ 22].
In vertebrates, the SWIRM domain is found fused along with a Myb (SANT) domain to a JAB1/PAD1 domain [ 48, 49] (for example, in the human protein KIAA1915, Figure 2).
Homologs of these molecules, with the SWIRM domain, are found in all eukaryotes belonging to the crown group, as well as earlier-branching protists such as the apicomplexans.
The availability of the crystal structure for the polyamine oxidase from maize allowed us to evaluate the sequence conservation of the oxidoreductase domain fused to the SWIRM domains [ 45, 46].
However, the common denominator in all these proteins are the SWIRM and Myb domains, suggesting that they mediate the evolutionarily conserved interactions of these proteins, such as those with the Swi2/Snf2 ATPase.