Words similar to svs-oh
Example sentences for: svs-oh
How can you use “svs-oh” in a sentence? Here are some example sentences to help you improve your vocabulary:
Calibration curves for both the SVS and the SVS-OH extracted from the area under the curve in the HPLC profile was linear in the range of 1-150 ng.
Based on the spiking of mouse plasma ex-vivo with known amounts of drug and subjecting the samples for the extraction procedure, the efficiency of drugs recovery was estimated to be 60-75% for SVS and 70-85% for SVS-OH.
While PTH demonstrated the expected anabolic effect on bone, SVS failed to stimulate bone formation, despite our verification by LC/MS of the active SVS-OH metabolite in mouse serum.
Similarly as described in the clinical trials, the early animal studies reported data supportive of the initial findings [ 1 4 5 6 33 34 ] . These results however, were not substantiated in later studies in rodents, where SVS had no or little effect on bone mineral density [ 26 ] . However, none of the studies has verified the actual presence of the active SVS-OH metabolite in the animal serum, as shown in this study.
The SVS-OH metabolite is first detectable in mouse serum by 10 minutes after gavage administration, and serum levels of SVS-OH continued to be observed by both mass-spectrometric and UV measurements through the last serum samples collected at 50 minutes post-gavage.