Example sentences for: svs-oh

How can you use “svs-oh” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The results suggest that Simvastatin does not enhance bone formation in this mouse model in vivo , despite our ability to verify the presence of the SVS-OH metabolite in mouse serum by LC/MS analysis.

  • Because SVS failed to have any effect on any static μCT parameter measured at either site in mouse femur, we conducted separate experiments designed to detect the presence of SVS-OH in mouse serum after SVS gavage by liquid chromatography/mass spectrometry (LC/MS).

  • Based on the spiking of mouse plasma ex-vivo with known amounts of drug and subjecting the samples for the extraction procedure, the efficiency of drugs recovery was estimated to be 60-75% for SVS and 70-85% for SVS-OH.

  • This report verifies the presence of the active SVS-OH metabolite in the mouse serum yet failed to demonstrate any beneficial effect on bone.

  • These data are in general agreement with studies in both rats and canines that calculate peak serum levels of SVS-OH at 40-60 minutes after gavage administration [ 18 ] . Thus, although we failed to document any bone anabolic activity of SVS in a mouse model of OVX-induced osteoporosis, LC/MS analysis of the SVS-OH metabolite in mouse serum document the efficacy of our gavage administration of SVS to experimental mice.


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