Words similar to surrogates

Example sentences for: surrogates

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The following sequence was used to obtain the HCV surrogates: 5'-biotin'AA UUG CCA GGA CGA CCG GGU CCU UUC UUG GAU CAA CCC GCU CAA UGC CUG GAG AUU-3'.
This non-random association between a surrogate and a target's pharmacologically active site assures a high degree of probability that, once found, surrogates will have utility for the rapid development of SDAs capable of identifying small molecules of pharmacological importance.
Interestingly, other amino acids in these surrogates were found to be identical to residues flanking the TxRLL motif in p170 on both the amino and carboxy sides (Figure 5).
If there is significant variation, assessment of intraspecific diversity can be based on a small sample of individuals only if individuals are sampled across existing population subdivisions for which geography and phenotypic variation are reasonable initial surrogates.
Additionally, the surrogates isolated in such studies would be prime candidates for phenotyping and target validation through their ability to regulate target activity and for identifying small molecule drug leads through their use in Site Directed Assays.