Example sentences for: surrogate

How can you use “surrogate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The weight matrix match is a surrogate for the energetic preference of a transcription factor for a particular sequence, and Ahab models the competition of several factors and their binding energies for a stretch of DNA (a module).

  • The concept that improvement as a measure of brain lesion volume is a proper surrogate outcome for destructive central nervous system diseases has been already accepted by academic and regulatory communities alike.

  • In this report, we questioned whether the EGFR acts as a surrogate scaffold during ERK activation through the δ-OR, as it appears to do for several other GPCRs [ 7 ] . To act as a surrogate-binding site for complex formation, the literature states that this protein must first become tyrosine-phosphorylated [ 7 ] . Tyrosine phosphorylation of the EGFR is apparent after agonist stimulation of the α 2 -AR (COS-7), β 2 -AR (COS-7), insulin-like growth factor (IGF-1; COS-7), substance P, and the lysophosphatidic acid receptor (LPAR) [ 7 ] . In addition, each of the aforementioned ligands also increases ERK phosphorylation when the proper receptor is expressed in these cell lines.

  • A structured interview is conducted by the study coordinator with each patient (case) or surrogate and each control subject to explain the study, obtain informed consent, and obtain standardized information on baseline medication and demographic, medical, social, and behavioral variables.

  • When the surrogate makes a sick joke and the guards erupt in laughter, the head guard, Paul Edgecomb (Tom Hanks), silences them worriedly.


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