Words similar to superinfection
Example sentences for: superinfection
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Replication-defective adenoviral vectors offer several advantages that make them attractive for gene delivery [ 3 4 5 6 ] . Adenoviral vectors are able to transduce proliferating or quiescent cells; they can accommodate dual, large insert sizes and can deliver additional genes by superinfection; and stable, high-titer viral stocks are easily generated [ 7 ] . Further, since the adenoviral genome is maintained extra-chromosomally, insertion site-dependent effects of the host genome are minimized, and exogenous genes can be reliably expressed at high levels.
Separate superinfection experiments of the BJAB-B1 cells were set up and were incubated with CMV for 5 hours to allow for viral attachment.
This study has shown that the BJAB-B1 and P3HR-1 cell lines were susceptible to a CMV superinfection, and a low amount of infection was observed.
Moreover, superinfection by a second viral strain has been documented in a number of individuals who have already mounted immune responses to the initial HIV infection.
Presence of the BZLF1 transcript in the superinfected P3HR-1 cells was observed beginning at 24 hours post superinfection, decreased at 48 hours and then was observed to increase after 72 hours (Figure 6B).