Example sentences for: supercoil

How can you use “supercoil” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The handedness of the initial double-strand helix is preserved throughout fiber morphogenesis suggesting that each cycle of supercoiling is a result of negative twist rather than simple over tightening of the previous helical form into a positive supercoil [ 5 ] .

  • • BTBD2 had little effect on the supercoil relaxation or DNA cleavage activity of TOP1 in vitro.

  • Coiled-coil domains are protein oligomerization motifs, which consist of two or more alpha helices that twist around one another to form a supercoil [ 1 ] . Peptides with the capacity to form coiled coils are characterized by a heptad repeat pattern in which residues in the first and fourth position are hydrophobic, and residues in the fifth and seventh position are predominantly charged or polar.

  • Cell growth continues beyond this point however forcing the fiber shaft to supercoil into a free standing helix that contracts into a ball-like form [ 6 ] . Filaments that grow on the surface of a ball can buckle and initiate the outgrowth of fibers that remain anchored to the ball surface [ 7 ] . These too supercoil when they reach a critical length or when they encounter an external impediment to their twisting.

  • To test the effect of BTBD2 on the supercoil relaxation activity of TOP1, HeLa cell nuclear extracts containing TOP1 were incubated with GST or GST-BTBD2 (aa 86-525).


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