Words similar to sulfinic

Example sentences for: sulfinic

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If no cysteinyl residue is nearby, the sulfenated cysteine can be further oxidized to sulfinic or sulfonic acid, or it can remain in the sulfenic acid state.
As mentioned above, proteins—in particular, the thiols of cysteines—are the major targets of H 2 O 2 . The reaction of cysteinyl thiolates with H 2 O 2 can lead to the formation of different modifications, such as sulfenic acid (–SOH), sulfinic acid (–SO 2 H), and sulfonic acid (–SO3H), as well as disulfide bond formation (–S–S–) and glutathione conjugation (–S–GSH) (Jacob et al.
All but the sulfinic and sulfonic acid modifications are readily reversible by reduction, using proteins such as thioredoxin or glutaredoxin; though sulfinic acid reductase activities have recently been identified in yeast and mammalian cells (denoted sulfiredoxin and sestrin, respectively) (Biteau et al.
Given the reversibility of thiol oxidations and the wide range of structural constraints that can be imposed by the formation of a sulfenic or sulfinic acid or a disulfide bond, we predict there will be many more examples of regulation by thiol modification.
By glutathionylating a single cysteinyl residue, the protein is protected from further oxidation of that cysteinyl residue to the irreversible sulfinic and sulfonic acid forms.