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Example sentences for: subtypes
How can you use “subtypes” in a sentence? Here are some example sentences to help you improve your vocabulary:
This is an advantage because ischemic stroke has a heterogeneous phenotype, and distinctions between specific clinical subtypes of ischemic stroke may be relevant [ 54 55 ] . To address the heterogeneity of the ischemic stroke phenotype, ischemic stroke is subtyped by a genotype-blinded adjudicator in both ISGS and SWISS.
Finally, when we explored this risk association among histological subtypes, significant risk reductions were apparent in when controls were compared to patients with both NSCLC and SCLC.
There are three subtypes of the alpha-2 adrenergic receptor: alpha-2A; alpha-2B; and alpha-2C [ 15 ] . The human alpha-2A subtype undergoes phosphorylation and short-term desensitization [ 11 12 ] , whereas the human alpha-2C subtype is not phosphorylated [ 16 ] and does not desensitize [ 11 ] . The human alpha-2C subtype, however, does undergo arrestin-dependent internalization [ 17 ] . Many studies [ 11 18 ] , including those from our laboratory [ 10 19 20 ] , have demonstrated agonist-induced down-regulation of alpha-2 receptors, although much less is known about the specific mechanisms for down-regulation as compared to the beta-2 receptor.
All three alpha-2 adrenergic receptor subtypes from nearly all species that have been tested undergo agonist-induced down-regulation [ 24 25 ] . Interestingly, we have shown that the potency of norepinephrine to produce down-regulation differs among alpha-2 receptor subtypes [ 19 24 ] . The concentration of norepinephrine required to produce half-maximal down-regulation is approximately 2 μM for the alpha-2A receptor.
These include the overall gene organization of the trp operon, for which many microbial patterns are known; the extremely rare gene order of trpEa trpEb instead of the typical order trpEb trpEa; the fusion of genes encoding the alpha ( trpAa ) and beta ( trpAb ) subunits of anthranilate synthase, a fusion that exists in only a limited number of other taxa, and the presence of operonic genes exhibiting distinctive homology subtypes ( aroA Iβ and tyrA (p) ).
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