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Example sentences for: subtypes
How can you use “subtypes” in a sentence? Here are some example sentences to help you improve your vocabulary:
In some cases, cancers that were assigned to a single diagnostic category by conventional morphological diagnostic methods have been found to have different gene expression profiles and belong to distinct molecular subtypes.
We propose that the conserved residues modulate the specificity of the predicted RNA interaction, and that the two subclades correspond to specificity subtypes within the larger family, possibly with unique functional features.
Distinct patterns of promoter methylation between SCC and AC, however, suggest that epigenetic pathways of tumor suppression may be different in these histologic subtypes.
The family of retinoic acid receptors includes those that bind only all-trans retinoic acid (RAR α,β,γ and those that bind either all-trans retinoic acid or 9-cis retinoic acid (RXR α,β,γ Since the transcriptional regulation of the retinoic acid ligand/receptor complex appears to involve the binding of receptor heterodimers (RAR/RXR), the specific cellular response may depend on the ratio of all-trans to 9-cis retinoic acid formed, as well as the expression of receptor subtypes.
All three alpha-2 adrenergic receptor subtypes from nearly all species that have been tested undergo agonist-induced down-regulation [ 24 25 ] . Interestingly, we have shown that the potency of norepinephrine to produce down-regulation differs among alpha-2 receptor subtypes [ 19 24 ] . The concentration of norepinephrine required to produce half-maximal down-regulation is approximately 2 μM for the alpha-2A receptor.
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