Example sentences for: substantiated

How can you use “substantiated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To the author's knowledge, no such comparison has yet been made, and the notion that the actual and the desired durations of exclusive breastfeeding differ has not been substantiated.

  • This subfamily assignment of individual TMC proteins was further substantiated by an analysis of the degree of conservation of intron positions within the Fugu rubripes TMC gene family (Figure 3B).

  • The functionality of the RhoA of A549 cells is substantiated by a number of previous studies, such as the need for RhoA in bradykinin-mediated activation of NF-kappa B [ 35 ] , and the abrogation of H 2 O 2 -mediated activation of JNK by RhoA antisense oligonucleotide [ 36 ] . Profilin purified from A549 cells is also indistinguishable from HEp-2 cell profilin, in terms its molecular weight, pI, affinity for poly-proline, and ability to stimulate actin-dependent transcription of RSV genome in vitro [ 11 ] . Thus, the inability of A549 cells to elicit actin stress fibers is likely due to an as yet unidentified factor or pathway that may be altered or missing in the A549 cells.

  • Similarly as described in the clinical trials, the early animal studies reported data supportive of the initial findings [ 1 4 5 6 33 34 ] . These results however, were not substantiated in later studies in rodents, where SVS had no or little effect on bone mineral density [ 26 ] . However, none of the studies has verified the actual presence of the active SVS-OH metabolite in the animal serum, as shown in this study.

  • Although some reporting alleges that Bin Ladin may have been an investor, or even had an operational role, in drug trafficking before 9/11, this intelligence cannot be substantiated.


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