Words similar to substantial

Example sentences for: substantial

How can you use “substantial” in a sentence? Here are some example sentences to help you improve your vocabulary:

Some investigators have intellectual property rights that may have very substantial financial value if the drug or device reaches the level of approval by the United States Food and Drug Administration.
Addition of cycloheximide has been shown to result in a substantial reduction in the elongation rate of protein synthesis in Dictyostelium and can cause mRNAs with few ribosomes to acquire more ribosomes, i.e., it can reverse the polysome shift [ 23 ] . Taken together, these findings suggest that countin mRNA is destabilized in developing ifkA null cells due to the loss of ribosomes and decreased translation efficiency of countin mRNA in these cells.
Following a similar approach in P. falciparum is most likely to provide substantial information about the many ORFs that lack functional annotation.
Litigation in Florida involving substantial claims may go on for six months to two or more years if the case goes to trial.
,”; but is there substantial enough evidence for these forms being spelled with a lower-case m to warrant such treatment?