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Example sentences for: su

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Also, the lipocalin-2 gene (LCN2) has been reported to be inducible by dexamethasone in murine cells [ 22 ] ; dexamethasone is one of the premedications administered to patients in the SU5416 arm.
The mouse homologue of one of the candidate biomarkers, LNC2, has been shown to be regulated at the transcriptional level by dexamethasone in murine cells [ 22 ] . However, there is no published evidence that the human LCN2 gene is likewise dexamethasone-inducible, and there is no description of glucocorticoid-responsive elements in the 5' regulatory region of the human LCN2 gene [ 28 ] . Further, preliminary investigation in our laboratory, using in vitro cultures of purified PBMCs from healthy volunteers, indicates that neither the LCN2 gene nor any of the other 3 transcripts is directly inducible by acute treatment with either SU5416 or dexamethasone (data not shown).
A set of 4 transcripts (CD24, lactoferrin, LCN2, and MMP-9) was identified, whose expression was significantly induced at the end of one treatment cycle relative to baseline following SU5416 administration.
Figure 1displays a schema of the DC scores assigned to each gene for each patient sample pair; all cases from the SU5416 arm show induction in at least 6 of the 13 genes.
The relative expression data for a selected subset of potential biomarkers were tested for differences between the SU5416 (treatment) and the standard of care (control) arms.