Words similar to stsl
Example sentences for: stsl
How can you use “stsl” in a sentence? Here are some example sentences to help you improve your vocabulary:
Recent linkage mapping studies mapped hypertension QTLs to a number of chromosomal regions in SHR and SHRSP rats [ 35 ] . Our FISH study assigned the STSL locus rat chromosome 6q12, a region where a cluster of blood pressure QTL with Lod score 4~6 has been reported to be present (M6MIT12-M6MIT3, 39 cM distance) in a New Zealand genetically hypertensive rat (GH rat) [ 35 ] . With respect to hypertension, although the SHR and SHRSP strains carry the Gly583Cys mutation, in extensive QTL mapping studies using these strains, no loci mapping to the rat STSL region have been reported [ 35 ] . In our study, the GH rat is neither sitosterolemic, nor has any nucleotide alteration at the STSL locus that would implicate this region as mutated.
Characterization of the rat STSL locus showed that it is highly conserved in organization, and maps to rat chromosome 6q12, a region also syntenic with the mouse and human STSL loci.
The WKY rat also carries this mutation and a high dietary intake of phytosterols will also increase the blood pressure and decrease the density of platelets, though to a lower extent than that observed in SHRSP rats [ 20 ] . These data support a pathological role of elevated plant sterols in these rats and support the notion that the STSL loci evolved to not only allow for the excretion of cholesterol into bile, but also to keep 'xeno-sterols' from accumulating in the body.
We sequenced the STSL loci in sitosterolemic and control rat strains and identified a number of nucleotide changes.
In this study, we report the gene structure organisation, cDNA and tissue expression patterns of rat Abcg5 and Abcg8 . Using fluorescence in situ hybridization, the rat STSL locus was assigned to the chromosomal 6q12.
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