Example sentences for: structure-function

How can you use “structure-function” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These include information relevant to structure-function relationships, specificity of therapeutic agents targeting protein kinases, and potential function of uncharacterized family members.

  • The BTB domain is a highly conserved 120 amino acid, hydrophobic-rich, protein-protein interaction domain that mediates homodimerization and heterodimerization of a large number of proteins with diverse functions [ 9 ] . The three dimensional structure of one BTB domain [ 33 ] has been characterized through structure-function studies [ 34 ] . Proteins containing BTB domains are currently categorized into three groups [ 35 ] : 1) DNA-binding proteins often containing zinc fingers in the C-terminal region, 2) actin binding proteins that contain a kelch repeat of ~50 residues that terminate in a pair of glycine residues [ 36 ] and 3) proteins that have neither an actin-binding domain nor a DNA-binding domain.

  • This type of limitation will decrease as our understanding of sequence-structure and structure-function relationships improves and as our knowledge of expression and cellular targeting in plants expands.

  • The putative E-loop region of the LGIC family of receptors is homologous to residues Y140 through K153 in the 5-HT 3 R [ 4 12 13 14 15 16 17 18 ] . Structure-function studies of this region have been conducted in several other members of this family of receptors including GABA A and nAChR subtypes.

  • Most importantly, in conjunction with robust heterologous expression and assay systems and high-throughput screening of odorant libraries, it will ultimately lead to understanding of structure-function relationships and small-molecule recognition by this large group of G-protein-coupled receptors.


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