Words similar to structure-function
Example sentences for: structure-function
How can you use “structure-function” in a sentence? Here are some example sentences to help you improve your vocabulary:
The BTB domain is a highly conserved 120 amino acid, hydrophobic-rich, protein-protein interaction domain that mediates homodimerization and heterodimerization of a large number of proteins with diverse functions [ 9 ] . The three dimensional structure of one BTB domain [ 33 ] has been characterized through structure-function studies [ 34 ] . Proteins containing BTB domains are currently categorized into three groups [ 35 ] : 1) DNA-binding proteins often containing zinc fingers in the C-terminal region, 2) actin binding proteins that contain a kelch repeat of ~50 residues that terminate in a pair of glycine residues [ 36 ] and 3) proteins that have neither an actin-binding domain nor a DNA-binding domain.
Such instability is consistent with known structure-function data regarding the importance of the C-terminus of Gα subunits.
These include information relevant to structure-function relationships, specificity of therapeutic agents targeting protein kinases, and potential function of uncharacterized family members.
It is to be mentioned that among all the Ser/Thr phosphatases, PP1 has been subjected to the most extensive structure-function analysis [ 19 20 21 22 23 24 25 26 ] . In fact, it was one of the first phosphatases for which the three-dimensional structure was solved [ 26 27 ] . A representative alignment in Fig.
Structure-function analysis of the NCoAs have revealed multiple copies of a signature motif, LXXLL, with conserved spacing that is required for interaction with nuclear receptors and CBP/p300 [ 99 101 ] . Intriguingly, different LXXLL motifs are required for PPARγ (Peroxisome Proliferator activated receptor γ, a gene down-regulated in Tat expressing cells; Acc# L07592, Table 1) function in response to different classes of ligands, suggesting distinct configuration of assembled complexes.
Loading...