Words similar to structure-based

Example sentences for: structure-based

How can you use “structure-based” in a sentence? Here are some example sentences to help you improve your vocabulary:

A combination of InterProScan and iGAP is under active development to integrate sequence- and structure-based annotation.
This has direct implications for structure-based function predictions using threading algorithms [ 6, 7].
This observation emphasizes the primary goal of structure-based screening procedures, which is to significantly accelerate the initial steps of lead identification projects by automatically discriminating between binders and non-binders, rather than ranking ligands according to their affinity for the receptor.
In recent years, it has become clear that the neuronal nAChR is a valid target against a variety of diseases, including cognitive and attention deficits, Parkinson's disease, anxiety, and pain management [ 3 4 ] ; the addiction liability and other undesirable side-effects of nicotine prohibit the use of this natural product for therapeutic applications, but the active development of nAChR agonists presenting adequate receptor subtype specificity should result in improved pharmacology and potency [ 4 ] . As for most membrane proteins, information on the 3 dimensional structure of the nAChR is limited, and the best experimental structure consists of 4.6 A data from electron microscopy [ 5 ] , a resolution that does not allow for structure-based design approaches.
Importantly, approximately 10 conserved residues that are detected in the structure-based alignments of the DPBB domains are also conserved in the RDRPs (Fig.