Words similar to structure-based
Example sentences for: structure-based
How can you use “structure-based” in a sentence? Here are some example sentences to help you improve your vocabulary:
Both of these structure-based approaches, used complementarily in conjunction with sequence-only motif-finding approaches [ 56 57 58 ] and experimental data, will enable to us better assign function to all or large parts of a proteome.
A combination of InterProScan and iGAP is under active development to integrate sequence- and structure-based annotation.
In recent years, it has become clear that the neuronal nAChR is a valid target against a variety of diseases, including cognitive and attention deficits, Parkinson's disease, anxiety, and pain management [ 3 4 ] ; the addiction liability and other undesirable side-effects of nicotine prohibit the use of this natural product for therapeutic applications, but the active development of nAChR agonists presenting adequate receptor subtype specificity should result in improved pharmacology and potency [ 4 ] . As for most membrane proteins, information on the 3 dimensional structure of the nAChR is limited, and the best experimental structure consists of 4.6 A data from electron microscopy [ 5 ] , a resolution that does not allow for structure-based design approaches.
This makes an even stronger argument for the integration of sequence- and structure-based annotation, to reduce the possibility of error propagation in electronic annotation.
This has direct implications for structure-based function predictions using threading algorithms [ 6, 7].