Example sentences for: ssz

How can you use “ssz” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • SSZ induced agranulocytosis is believed to be mediated by immunological hypersensitivity of myeloid precursors [ 38 ] . Spontaneous recovery from SSZ agranulocytosis is frequently seen, although fatalities have been reported and some patients may benefit from granulocyte macrophage-colony stimulating factor [ 39 40 ] .

  • Both severe hepatitis and acute liver failure have been attributed to SSZ [ 25 26 27 28 ] . Patients with SSZ hepatotoxicity demonstrate a prompt recurrence of symptoms upon rechallenge with SSZ or sulfonamide [ 15 29 30 31 ] . Susceptibility to the toxic effects of SSZ and other sulfonamides may be due to the interaction of metabolic pathways regulating N-acetylation and specific detoxification of the metabolites of the drug [ 32 33 ] . However, it remains unclear if genetic differences in drug metabolizing enzyme expression may increase the risk of SSZ toxicity.

  • Liver biochemistries were normal immediately before and two weeks after initiating SSZ.

  • The use of steroids in the setting of SSZ toxicity is controversial and not always effective.

  • To our knowledge, only one other case of a systemic granulomatous reaction to SSZ has been reported which improved within 24 hours of SSZ discontinuation [ 18 ] . In other cases of granulomatous drug reactions, multi-organ involvement with fevers and eosinophilia have been reported [ 19 20 ] .


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