Words similar to ssz
Example sentences for: ssz
How can you use “ssz” in a sentence? Here are some example sentences to help you improve your vocabulary:
Both severe hepatitis and acute liver failure have been attributed to SSZ [ 25 26 27 28 ] . Patients with SSZ hepatotoxicity demonstrate a prompt recurrence of symptoms upon rechallenge with SSZ or sulfonamide [ 15 29 30 31 ] . Susceptibility to the toxic effects of SSZ and other sulfonamides may be due to the interaction of metabolic pathways regulating N-acetylation and specific detoxification of the metabolites of the drug [ 32 33 ] . However, it remains unclear if genetic differences in drug metabolizing enzyme expression may increase the risk of SSZ toxicity.
Our patient developed a severe systemic illness following three weeks of SSZ therapy for rheumatoid arthritis.
Three weeks after starting SSZ, the patient developed an erythematous rash over the upper extremities and trunk that improved with cetirizine (Zyrtec, Pfizer Inc, New York, NY).
Although rheumatology patients may be at increased risk of SSZ toxicity compared to IBD patients, there are no reliable laboratory or clinical predictors of SSZ toxicity [ 45 ] . Therefore, practicing physicians should be aware of the potential for severe, unexplained granulomatous reactions to SSZ that can mimic other infectious, malignant, and autoimmune conditions.
The presumed mechanism of liver injury in SSZ hepatotoxicity is an idiosyncratic hypersensitivity response.