Words similar to ssz
Example sentences for: ssz
How can you use “ssz” in a sentence? Here are some example sentences to help you improve your vocabulary:
SSZ induced agranulocytosis is believed to be mediated by immunological hypersensitivity of myeloid precursors [ 38 ] . Spontaneous recovery from SSZ agranulocytosis is frequently seen, although fatalities have been reported and some patients may benefit from granulocyte macrophage-colony stimulating factor [ 39 40 ] .
Both severe hepatitis and acute liver failure have been attributed to SSZ [ 25 26 27 28 ] . Patients with SSZ hepatotoxicity demonstrate a prompt recurrence of symptoms upon rechallenge with SSZ or sulfonamide [ 15 29 30 31 ] . Susceptibility to the toxic effects of SSZ and other sulfonamides may be due to the interaction of metabolic pathways regulating N-acetylation and specific detoxification of the metabolites of the drug [ 32 33 ] . However, it remains unclear if genetic differences in drug metabolizing enzyme expression may increase the risk of SSZ toxicity.
Liver biochemistries were normal immediately before and two weeks after initiating SSZ.
The use of steroids in the setting of SSZ toxicity is controversial and not always effective.
To our knowledge, only one other case of a systemic granulomatous reaction to SSZ has been reported which improved within 24 hours of SSZ discontinuation [ 18 ] . In other cases of granulomatous drug reactions, multi-organ involvement with fevers and eosinophilia have been reported [ 19 20 ] .
Loading...