Words similar to sscp

Example sentences for: sscp

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Existing procedures for detection of point mutations include SSCP (single strand conformational polymorphism) [ 11 12 ] , a variation of SSCP called DOVAM (Detection of Virtually All Mutations) [ 19 ] , Enhanced SSCP [ 28 ] , HA (Heteroduplex Analysis) [ 13 14 ] , PTT (Protein Truncation Test) [ 15 ] , DGGE (Denaturing Gradient Gel Electrophoresis) [ 16 17 18 ] , chemical cleavage of mismatch [ 20 ] , and RNase cleavage [ 21 ] . Each of these procedures has its advantages and limitations but the size of the gene and the cost of the procedures have not made them routine in most laboratories.
All twelve exons of LMNA were screened by denaturing high performance liquid chromatography (DHPLC) and single strand conformation polymorphism (SSCP) (Figure 4).
An additional 98 unrelated subjects with dilated cardiomyopathy were screened by SSCP and DHPLC and found not to carry the 908_909delCT mutation.
Single-stranded conformational polymorphism (SSCP) analysis
Although in this report using this technique we were able to detect a single nucleotide mutation in a PCR product of 390 bp, most laboratories would suggest that SSCP detects approximately 70 to 80% of mutations.