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Example sentences for: ssaps

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Contextual information from gene neighborhoods provides details regarding functional interactions of the SSAPs with DNA recombination pathways
Thus, the same or analogous operon organizations may emerge convergently on multiple occasions, probably due to the selective pressure arising from the strong interactions between the SSAPs and their functional partners such as SbcC, SSB and LE.
Likewise, the observation that, in one or more cases, genes encoding each of the SSAPs co-occur in the same predicted operon with SSB or a λ-type exonuclease, suggests that similar operon structures may also emerge independently in evolution.
The clustering of functionally related genes in prokaryotic genomes into co-transcribed and co-regulated units, operons, often allows functional assignments through the principle of 'guilt by association' [ 30 31 32 ] . Generally, genes whose products physically interact to form a complex or are involved in successive steps in a biochemical pathway form operons that are conserved over large evolutionary distances [ 30 ] . On previous occasions, we have used gene neighborhoods or operons to predict novel DNA repair complexes and their components [ 33 ] . Accordingly, a similar approach was applied to the three families of SSAPs (RecT/Redβ, ERF, Rad52), to shed light on their functional links.
By comparing the gene neighborhoods of the SSAPs, we show that the predicted operons that include the SSAP genes evolve according to the "LEGO" principle.