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Example sentences for: sporadic
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Foodborne outbreaks of cryptosporidiosis in which the vehicle of transmission was identified are few and only one outbreak in Maine was definitively associated with contaminated fresh-pressed apple cider [ 28 ] . Other foodborne outbreaks due to cryptosporidiosis have implicated food handlers [ 29 ] and social events [ 30 31 ] . Person-to-person outbreaks have been better documented, such as those in hospitals [ 32 33 34 35 36 37 ] and day care centers [ 38 39 ] . It is becoming increasingly evident that cryptosporidiosis is one of the multitude of enteric pathogens that is endemic in hospital and day care settings [ 40 41 42 43 ] . Other routes of exposure to Cryptosporidium may be responsible for sporadic disease in the general population such as specific sexual contact with an infected individual [ 44 45 46 ] , travel to endemic countries [ 47 48 49 50 ] , and contact with animals, both domestic and livestock [ 1 2 51 52 ] . Recent studies in Australia have demonstrated that exposure to persons with diarrhea and swimming in public pools rather than consumption of untreated tap water are the sources of community-acquired cryptosporidiosis in that country [ 53 ] . The relative contribution for each of these modes of transmission to the total burden of sporadic cryptosporidiosis among immunocompetent persons continues to be unknown in the U.S.
Lastly, sporadic individuals with classic CFEOM were screened for ARIX mutations.
The sporadic distribution of this family among phylogenetically distant bacteria, along with its presence in several prophages, suggests that, like the RecT/Redβ and ERF superfamilies, at least the bacterial RAD52-proteins might be of predominantly phage origin.
None of these sequences are known to predispose to genomic rearrangements, although short stretches of identical sequence are often found at the sites of germline translocation and deletion breakpoints [ 20 21 22 ] . Genomic analysis of the parents and siblings of Case 2 indicated that the mutation was sporadic.
Liver biopsy showed intralobular cellular infiltrates consisting of macrophages and eosinophils as well as sporadic eosinophilic cell necroses; virology was negative.
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