Example sentences for: spike-skew

How can you use “spike-skew” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The F smetric, which uses a single standard curve pooled from each dataset to normalize all arrays in that dataset, effectively eliminated spike-skew effects.

  • AD sand F smetrics performed equally well and best overall, with accuracies above 99% regardless of spike-skew.

  • Accuracy was defined as the fraction of computed fold-changes that were accurate within twofold, and determined for assumed levels of spike-skew from 10-40% (percentage is the ratio of standard deviation (SD) to mean of the random spike-skew term in the simulation).

  • Nevertheless, the simulations demonstrate that at levels of spike-skew consistent with our experience, scaled frequency is as accurate as globally normalized AD s; this observation is robust to changes in the model parameters.

  • In the simulations, a spike-skew level of 20% led to MEDACV values for frequency in simulated replicates that were much higher than those of AD sor F s.


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