Example sentences for: spike-in

How can you use “spike-in” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Experiments using 0.1 to 10 μg cRNA per hybridization with corresponding amounts of spike-in transcripts, as well as high and low gain settings on the scanner, indicated that readout saturation (not hybridization saturation) accounted for most of the observed curvature in the spike-in response.

  • Then a linear model (with zero intercept) was fitted to the pooled AD svalues for the 11 spike-in transcripts from all arrays, ignoring negative AD svalues or those associated with Marginal/Absent Absolute Decisions.

  • Our 'spike-in' normalization method, which we call 'frequency normalization', uses spiked transcripts for two purposes.

  • The specific hybridization intensity (AD) value for each of the 11 spike-in controls is plotted as a function of transcript frequency in units of transcripts per million.

  • Our results suggest that there is significant uncertainty in the molar ratio of spike-in mRNAs to template-derived cRNAs in any hybridization (the spike-skew effect).


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