Words similar to sod
Example sentences for: sod
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In small vacuoles, SOD1 aggregates overlap with cytochrome c signal (see Fig.
Non-transgenic littermates of SOD G93Atransgenic mice were used as wild type controls (WT mice).
Of the FALS cases about 20% are due to mutations in SOD1 [ 4 ] . Rodents transgenic for mutant human SOD1 develop progressive skeletal muscle atrophy, paralysis and death similar to human cases [ 5 6 7 8 ] . The disease causing property of mutant SOD1 is independent of the normal SOD1 activity, and thus, mutant SOD1 kills motor neurons by gaining a toxic property (reviewed in [ 9 10 ] ).
The plateau at low concentrations corresponds to the fluorescence signal in the Cy5 (red) channel approaching the background, indicating a detection limit of about 5 ng/ml for SOD and MAP4.
Intense SOD1 signal is located both at the boundary of the vacuoles and inside (Fig.