Words similar to socs

Example sentences for: socs

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Another class of compounds known as imidazoles, of which SKF 96365 is the best studied, have also been shown to block MTX-induced responses in many cell types [ 5 7 12 28 ] . The imidazoles, which are antifungal agents that inhibit cytochrome P 450 , are relatively non-selective and are known to block voltage-gated Ca 2+channels and receptor-activated Ca 2+influx through so-called store-operated channels (SOCs) [ 29 ] , but their mechanism of action in this regard remains unknown.
[ 8 ] showed that SOCs in pancreatic β-cells have characteristics essentially identical to channels activated by MTX in the same cell type.
This result was confirmed by electrophoretic mobility shift assays and the absence of detectable amounts of the STAT1 antagonists SOCS1 and SOCS3 (data not shown).