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Example sentences for: sis
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Two additional gene groups whose functions are linked to the process of protein synthesis were present among the trophozoite genes: five DEAD-box RNA helicases, including a close homolog of P. cynomolgi RNA helicases-1 [ 41] and 23 molecular chaperone-like molecules, including two P. falciparum heat-shock proteins such as PfHSP70 (GenBank accession number M19753) and PfHSP86 (accession number L34028), and a homolog of a DnaJ-domain-containing protein family, DNJ1/SIS1 homolog [ 42].
Isolation of the sis5-1/abi4-101 mutant of Arabidopsis thaliana var.
The sis5-1/abi4-101 mutant is resistant to the inhibitory effects of glucose on seed storage lipid mobilization
Several groups of Arabidopsis mutants that are resistant to the inhibitory effects of high sugar concentrations have been isolated [ 46 47 48 49 50 ] . Characterization of these mutants reveals that the sis5 [ 46 ] , sun6 [ 50 ] , gin6 [ 49 ] and isi3 [ 45 ] mutants are allelic to the abscisic acid insensitive mutant abi4 [ 51 ] and the sis4 [ 46 ] , isi4 [ 45 ] and gin1 [ 45 ] mutants are allelic to the abscisic acid biosynthesis mutant aba2 [ 52 ] . In addition, the ethylene constitutive response mutant ctr1-1 [ 53 ] , as well as the ethylene-overproduction mutant eto1 [ 54 ] , display sugar-resistant phenotypes [ 48 ] . Conversely, the sugar-response mutant sis1 exhibits an ethylene constitutive response phenotype and is allelic to ctr1-1 [ 47 ] . The prl1 mutant, which exhibits increased sensitivity to exogenous sugars [ 55 56 ] , carries a mutation in a gene that encodes a WD protein that interacts with SNF1 protein kinases [ 57 ] .
A number of Arabidopsis sugar-response mutants have been isolated that, unlike wild-type plants, are able to develop substantial shoot systems in the presence of 0.27 to 0.33 M sucrose or glucose [ 46 47 48 49 50 ] . Analysis of a representative mutant of this type, the sis5-1/abi4-101 mutant [ 46 ] , reveals that it is resistant to the inhibitory effects of exogenous glucose on seed storage lipid breakdown.
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