Words similar to sirna

Example sentences for: sirna

How can you use “sirna” in a sentence? Here are some example sentences to help you improve your vocabulary:

(Details of the structure and function of the RISC are still largely unknown, but it is thought to act as a true enzyme complex, requiring only one or several siRNA molecules to degrade many times that number of matching mRNAs.)
The serendipitous success of the human siRNA against rat profilin suggested that small mismatch(es) may be tolerated in RNA interference, the details of which will be published elsewhere.
Interestingly, perfect or near-perfect target complementarity is associated with mRNA degradation [ 24 25 26 ] , similar to the effects of siRNA, whereas imperfect base-pairing is associated with regulation by translational inhibition [ 6 27 ] . Recently, siRNAs with imperfect match to target mRNA were observed to function as translational inhibitors [ 28 ] , suggesting that the type of 21-22 nucleotide RNA-mediated regulation may be largely determined by the quality of target complementarity.
Usman of Sirna is confident they will be.
Post-transcriptional gene silencing using synthetic short interfering RNA (siRNA) molecules has been recently used to ablate specific mRNAs and thus, produce phenotypic mutations in specific genes [ 16 17 ] . We have adopted this technology to knockdown specific gene products in RNA viruses that are obligatory intracellular parasites [ 18 ] . In the present study, we have successfully used a similar strategy to generate phenotypic PP1-deficient P. falciparum parasites.