Words similar to single-stranded
- single-key
- single-nucleotide
- single-parameter
- single-piece
- single-purpose
- single-step
- single-story
- single-strain
- single-strand
- single-strand-binding
- single-stranded
- single-subject
- single-subunit
- single-survey-response
- single-symbiosis
- single-temperature
- single-tube
- single-unit
- singled
- singles
- singleton
Example sentences for: single-stranded
How can you use “single-stranded” in a sentence? Here are some example sentences to help you improve your vocabulary:
As a result, Top67 could position itself in the absence of ZD domain at the junction of double- and single-stranded DNA for subsequent DNA cleavage, as previously observed for intact topoisomerase I [ 8 ] . Reversal of DNA cleavage also took place readily with Top67 upon addition of 1 M NaCl and 4 mM MgCl 2 . The ZD domain also was not required for selectivity of a cytosine in the -4 position relative to the cleavage sites.
The structure of this 67 kDa domain has been determined by X-ray crystallography to be torus-like, indicating the need for protein conformational change for strand passage to take place after DNA cleavage [ 4 ] . Relaxation activity requires the presence of the Zn(II) binding tetracysteine motifs [ 5 ] found between the 67 kDa N-terminal domain (Top67) and the 14 kDa C-terminal single-stranded DNA binding domain (Figure 1).
The Northern blots were probed using single-stranded internally labeled DNA probes as described previously [ 6 ] . Membranes were re-probed and hybridized with 32P-labeled probe encoding 18S ribosomal RNA and all signals were normalized to this 18S signal upon quantification.
Two complementary molecules of single-stranded DNA have paired bases that bond with each other and form the well-known double helix structure.
The results indicated that Top67 was effective in binding to both double-stranded and single-stranded DNA.
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