Example sentences for: single-stranded

How can you use “single-stranded” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This result indicated that with regard to the mechanism of E. coli topoisomerase I, the ZD domain was likely to function as a single-stranded DNA binding domain instead of having double-stranded DNA binding function as previously suggested [ 21 ] . Even though Zn(II) binding transcription factors that recognise specific double-stranded DNA are well represented in eukaryotes [ 23 24 ] , there are also numerous examples of Zn(II) coordination being required for interaction with single-stranded nucleic acid or damaged DNA with single-strand characteristics [ 24 25 26 27 ] .

  • Before moving on, a quick course in molecular biology: All living creatures, from viruses on up, pull off the feat of self-replication by encoding the necessary information in nucleic acids--in particular the double-stranded DNA discovered by Crick and Watson or, for a few renegade viruses, single-stranded RNA or even single-stranded DNA.

  • The gel mobility shift assay was used to compare the binding affinities of Top67 and the ZD domain to a 5' end-labeled single-stranded oligonucleotide 35 base in length.

  • A substrate with both single-stranded and double-stranded regions was constructed to mimic such junction in negatively supercoiled DNA.

  • ZD domain was found to bind to single-stranded DNA, but not double-stranded DNA, with high affinity.


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