Example sentences for: single-strand

How can you use “single-strand” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • An NMR structural analysis of the HRD domain of Sgs1p and models for the WRN and BLM domains suggests that this region is a single-strand nucleic acid binding domain that functions as an accessory DNA binding region with the helicase domain [ 41].

  • This result indicated that with regard to the mechanism of E. coli topoisomerase I, the ZD domain was likely to function as a single-stranded DNA binding domain instead of having double-stranded DNA binding function as previously suggested [ 21 ] . Even though Zn(II) binding transcription factors that recognise specific double-stranded DNA are well represented in eukaryotes [ 23 24 ] , there are also numerous examples of Zn(II) coordination being required for interaction with single-stranded nucleic acid or damaged DNA with single-strand characteristics [ 24 25 26 27 ] .

  • The relative orientation of transcription was assessed by restricting which primers were present during the reverse transcriptase (RT) single-strand synthesis step of the reaction.

  • The ZD domain interacts with the passing single-strand DNA to be transported (T-strand).

  • The cycling parameters were as follows: (1) 50°C × 30 min, reverse transcription single-strand synthesis (with one, both or neither primer); (2) 95°C × 15 min, activate AmpliTaq polymerase, inactivate RT enzymes; (3) 4°C, add missing primers; (4) 94°C × 30 sec, commence PCR cycling; (5) 56°C × 30 sec; (6) 72°C × 30 sec; (7) go to step 4 (30 cycles in total); (8) 72°C × 10 min.


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