Example sentences for: simplify

How can you use “simplify” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The mutagens permit direct selection of clones in which cellular genes have been disrupted and simplify the characterisation of genes associated with recessive mutations [ 1 ] . Mutagenesis of embryo-derived stem (ES) cells, coupled with in vitro genetic screens, has been widely used to analyse gene functions in mice [ 1 ] . These have included screens for mutations in developmentally regulated genes [ 2 3 4 5 ] , in genes regulated by extracellular agonists [ 6 7 ] , and in genes encoding secreted and transmembrane proteins [ 8 9 ] . Characterized mutations include genes involved in intracellular trafficking [ 10 ] , transcriptional regulation [ 11 12 ] , signal transduction [ 7 8 11 13 14 15 ] , neural development [ 16 ] and neural wiring [ 17 ] , and axial patterning [ 18 19 ] . The rapid expansion of the nucleic acid databases has had a tremendous impact on the identification of genes disrupted by gene entrapment.

  • In order to simplify the Figures, only the results for two large V H families (V H 1 and V H 3) and two small V H families (V H 5 and V H 6) are provided, although assays for each V H family and each major CH family (μ,γ, and α) were performed and revealed similar findings.

  • To simplify comparisons across HRQOL dimensions, we report results for models including all predictor variables, regardless of whether any individual variable was predictive of the outcome.

  • As I describe the different regulatory programs, I think you will understand why we believe it is time to simplify.

  • To determine which nucleotide sequences are most important for core origin and enhancer function, we constructed consecutive ~50-bp deletions throughout extended ars3002 . To simplify production of these deletion mutants, we destroyed the Eco RI site between the core ars3002 and the enhancer and introduced a Cla I linker (see Materials and Methods).


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