Example sentences for: signal-to-background

How can you use “signal-to-background” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The spots were detected with similar signal-to-background ratios until the end of the time course (96 h after induction) for lines EL702C and E, whereas line EL700S did not show any spots during this time course.

  • As plants contain chloroplasts in leaf and stem cells and many autofluorescent compounds are localized in cell walls, a signal-to-background ratio for GFP detection is probably lower than in animal systems.

  • The average signal-to-background ratios across all hybridizations for these negative control spots was less than twofold, which is well below the conservative fivefold signal-to-background threshold used to filter data (see Materials and methods).

  • Methods used to determine a signal threshold include the use of arbitrary fluorescence intensities [ 19 ] , relative errors in Cy3/Cy5 ratios [ 9 20 21 ] or certain signal-to-background ratios [ 22 ] . However, these methods lack information about the specificity and sensitivity of the threshold, which are crucial parameters for estimation of the diagnostic accuracy of microarray hybridizations.


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