Words similar to signal-regulated
Example sentences for: signal-regulated
How can you use “signal-regulated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Cellular response to chronic TLK286 exposure included a two-fold decrease in GSTP1-1 protein levels, confirming a GSTP1-1 mediated mechanism of activation [ 7 ] . Mouse embryo fibroblast cells from GSTP1-1 deficient animals elevated the expression of signal-regulated kinases ERK1/ERK2 and reduced the doubling time of cell proliferation [ 8 ] . That paper also found that a clone of HL60 cells resistant to TLK199, an inhibitor of GSTP1-1, has been shown to have elevated activities of c-Jun NH 2 -terminal kinase (JNK) and ERK1/ERK2.
Immunoblotting of membranes for phospho-MAPK (extracellular signal-regulated kinase [Erk]1/2) was performed using a Phospho-MAPK Antibody Sampler kit (Cell Signaling, Beverly, MA, USA) according to the manufacturer's instructions.
However, the signal transduction pathway, MAPK, has been shown to control and be upstream of DNA-replication, transcription, and cell cycle pathways [ 52 53 54 ] . The mitogen-activated protein kinase (MAPK) pathway, consisting of the MAP kinase kinases (MKKs) 1 and 2, and extracellular signal-regulated kinases (ERKs) 1 and 2, which have been implicated in diverse cellular processes including proliferation, transformation, and cell differentiation [ 53 ] . The MAP kinase (MAPK) pathway has emerged as a crucial route between membrane-bound Ras and the nucleus.
The mitogen-activated protein kinase (MAPK) family consists of three commonly recognized subgroups: the extracellular signal-regulated kinase (ERK), the c-jun-N-terminal kinase (JNK), also known as the stress activated protein kinase (SAPK) and the p38 kinase.
In addition, the TCFs have been found to be targets for all three families of MAPKs: the extracellular signal-regulated kinases 1/2 (ERK1/2), the jun-N-terminal kinases/stress activated protein kinases (JNK/SAPK), and the p38 kinase [ 17, 18].
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