Words similar to side-chain
Example sentences for: side-chain
How can you use “side-chain” in a sentence? Here are some example sentences to help you improve your vocabulary:
V29A reduces the size of the side-chain, asking whether Val29 approaches the A's closely enough to provide a stacking-like interaction.
[ 32 35 38 ] The structural similarity between known MHC alleles allows for side-chain prediction procedures to be carried out for other MHC molecules using available structural templates.
Development of an efficient energy function for the accurate prediction of both backbone and side-chain conformations followed by an effective MHC-peptide interaction function will help to quantify the differences in peptide binding caused by MHC polymorphism and peptide diversity.
The side-chain of Phe144 contacts the ligands only via its c-alpha an c-beta atoms, and similar interaction can occur with a leucine or glutamine at this position; however, while the conformation presented is projecting away from the ligands, alternative conformers could bring the side-chain closer to the agonists, and represent structural determinants for specificity.
This implies that the backbone atoms in the MHC molecules play a secondary role in the binding of the peptide; it is the interaction between the sidechain atoms in the MHC molecules with both side-chain and backbone atoms in the peptide what determines the binding.