Words similar to shbg-bound

Example sentences for: shbg-bound

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Several active research programs are investigating the risk associated with serum estrogens, gonadotropins and urinary sex hormone metabolites for a variety of diseases including breast cancer [ 1 ] , endometrial cancer [ 2 ] , and osteoporosis [ 3 ] . The results of the few published studies suggest that the natural temporal variability (true variation over time, not variation due to storage or other factors) of some serum estrogens, gonadotropins and urinary sex hormone metabolites is sufficiently great that a single measurement occasion may be inadequate to ensure a reliable estimate [ 4 5 6 ] . Published intraclass correlation coefficients (ICC) vary between 0.06 and 0.62 for estradiol (E 2 ) and between 0.52 and 0.69 for estrone (E 1 ) [ 4 ] . Only the percent of free E 2 and of SHBG-bound E 2 have been found to be sufficiently reliable to account for as much as 50% of the variance in the true mean ( ICC > 0.7).