Example sentences for: sh

How can you use “sh” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It has been proposed that Src kinases activate Btk through phosphorylation of a tyrosine, Y551 in the activation loop of Btk, leading to increased kinase activity and autophosphorylation of a tyrosine in the SH3 domain.

  • A DALI search [ 20] of the PDB database with this β-barrel revealed no specific structural relationships with other folds such as the OB fold or the SH3-like barrel beyond the presence of curved β-sheets, suggesting that it represents a domain with a distinct fold (Figure 2).

  • In contrast, a mutation in the SH3 domain prevents Boi1 from localizing to necks, but it does not diminish the ability of Boi1 to localize to buds.

  • It has recently been suggested that G-protein coupled receptors with PDZ domains, SH2-containing domains and PTB domains participate in protein-protein interactions with partners other than G-proteins, such as Grb2 and JAK2, which may allow these receptors to bypass the G-proteins and utilize other signaling cascades (29).

  • These data indicate that the v-crk SH2 domain interacts with the C-terminal YDXP motifs, and as suggested by Birge et al, v-crk may be able to protect them from dephosphorylation and/or induces their phosphorylation [ 12 ] . They also suggest that the YQXP motifs may be involved in binding to other intracellular signaling molecules.


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