Words similar to serpins

Example sentences for: serpins

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Proteins, such as serine proteases and their inhibitors, could alter the quality of this highway and thus play critical roles in migratory processes [ 1 ] . Members of the serine protease inhibitor superfamily, or serpins, act by binding to and permanently inactivating their target protease(s).
Since a proline occurs not only in position 357 of PAI-1, but also in the corresponding position of several other serpins (Table 1) we attempted to find out how does a mutation of P357 affect the inhibitory activity of PAI-1.
[ 14 15 ] Since many serpins with identical amino acid residue at P1 position display different specificities, it is unlikely that the P1 residue is the sole determinant for target protease specificity, other regions of PAI-1 may also affect its specificity toward target proteases.
Although avian and mammalian serpins are members of the same superfamily, they are evolutionarily distinct [ 38 ] . This divergence likely accounts for the species specificity of the PN-1 antibody.
While in PAI-1 this position accommodates a negatively charged aspartic acid residue, in other serpins it sometimes accommodates its non charged analog asparagine (Table 1).