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Example sentences for: serines

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When recruited to stalled transcription complexes, P-TEFb phosphorylates serines at position 2 in the CTD [8], the Spt5 subunit of DSIF [9], and the RD subunit of NELF [10].
While phosphorylation of serines 15 and 20 of p53 are clearly dependent on the ATM and chk2 protein kinases [ 10, 11, 12, 13, 14], the kinases responsible for phosphorylation of the remaining serine residues in vivo is not clear.
The opossum alpha-2C adrenergic receptor has a very similar acidic serine motif (EESSTSE) in the third intracellular loop (Figure 1; [ 21 ] ), whereas the human alpha-2C receptor has a DESSAAAE sequence in the same region (Figure 2; [ 22 ] ). Thus, we postulated that the lack of down-regulation in the human alpha-2C was related to having only two rather than four serines in the motif, and furthermore that the ability of the opossum alpha-2C to undergo down-regulation was dependent on having all four serine/threonine residues in the EESSTSE motif.
ATM therefore controls the phosphorylation of serines 15 and 20 of p53.
Next, the GTF TFIIH unwinds the DNA, opens the transcription bubble, and phosphorylates serines at position 5 in the C-terminal domain (CTD) of the RPB1 subunit of RNAPII (reviewed in [2]).