Words similar to ser
Example sentences for: ser
How can you use “ser” in a sentence? Here are some example sentences to help you improve your vocabulary:
Primer pair P316F/P316R was designed to replace the Asn57 A A T codon with the Ser A G T codon (Table 1).
To better understand the regulation of cPLA 2 by the MEK1/ERK pathway and Ca 2+, we investigated the effect of MEK inhibitors on AA release, cPLA 2 phosphorylation of Ser 505, cPLA 2 translocation kinetics, and [Ca 2+] i increase in Madin-Darby canine kidney (MDCK) cells.
Our prior studies showed that increases in cGMP by nitrovasodilators and cAMP by forskolin increase ser 16-HSP20 phosphorylation and induce force suppression [ 8 ] . Such results suggest that the correlation between ser 16-HSP20 phosphorylation and force suppression is robust in the swine carotid stimulated with 10 μM histamine.
Because Val and Met are both non-polar amino acids, and Ser and Gly are both polar and uncharged amino acids, those amino acid substitutions between ZAS-N and ZAS-C may result in minor changes in the tertiary structure of the zinc fingers which account for the subtle differences in the DNA binding properties of the ZAS-N and ZAS-C domains.
In vitro studies have demonstrated that dephosphorylated cPLA 2 is catalytically active and that Ser 505phosphorylation increases activity by only ~30 percent [ 24 ] . In contrast, cells expressing the cPLA 2 S505A mutation fail to release AA in response to a low dose of calcium ionophore, but release similar amounts of AA as cells expressing wild-type cPLA 2 in response to high dose ionophore [ 22 ] . From these studies, it has been suggested that cPLA 2 Ser 505phosphorylation may have a role in regulating translocation [ 22 ] . A previous study demonstrated translocation of cPLA 2 S505A in response to Ca 2+ionophore, but did not address the kinetics of translocation, translocation in response to a physiological agonist, or differences in targeting [ 25 ] .
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