Example sentences for: sequestration

How can you use “sequestration” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The effects of specific RXR ligands on the CAR/RXR heterodimer have not been characterized, although high concentrations of both 9-cis-RA and all-trans retinoic acid have been reported to block PB induction of the CAR targets CYP2B1 and CYP2B2 in primary rat hepatocytes [ 17 ] . In addition, a recent report suggests that both compounds decrease TCPOBOP-dependent CAR transactivation [ 18 ] . In both cases, these effects were primarily attributed to sequestration of limiting amounts of RXR into ligand-dependent homodimers or heterodimers with other receptors.

  • The reason for the clearance of circulating cells immediately following IL-2 administration remains unsolved, and may be related to their sequestration in the reticular endothelial system, a hypothesis that could not be evaluated by this study.

  • If the Hsp70 in these aggregates retains the capacity to bind GR, this could account for the sequestration of nascent GR in these structures.

  • Experiments with cell lines show that tumor cells can bind soluble OPN and can migrate towards an OPN concentration gradient [ 8 19 ] ; sequestration from the extracellular matrix in vivo is thus pertinent.

  • These effects are more pronounced under general anaesthesia because of the larger blood sequestration into the peripheral higher compliant venous system, as a result of the loss in the muscular and vascular tone induced by the anaesthetic drugs [ 1, 2].


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