Example sentences for: sequestration

How can you use “sequestration” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The effects of specific RXR ligands on the CAR/RXR heterodimer have not been characterized, although high concentrations of both 9-cis-RA and all-trans retinoic acid have been reported to block PB induction of the CAR targets CYP2B1 and CYP2B2 in primary rat hepatocytes [ 17 ] . In addition, a recent report suggests that both compounds decrease TCPOBOP-dependent CAR transactivation [ 18 ] . In both cases, these effects were primarily attributed to sequestration of limiting amounts of RXR into ligand-dependent homodimers or heterodimers with other receptors.

  • For example, it is possible that the inhibitory effect of LG1069 in the stable CAR expressing cell line is based on the sequestration of limiting amounts of RXR into ligand-dependent homodimers, as has been suggested in previous studies using primary hepatocytes [ 17 ] . However, similar effects were observed with the relatively large amounts of RXR used for the biochemical studies or with the transient transfections, which relied on cotransfected RXR.

  • Our earlier findings including a reduced number of elongated spermatids in the ABP-TG mice [ 26 ] also support the notion that higher than physiological concentrations of ABP affect spermatogenesis indirectly, through sequestration of androgens; the transformation of round spermatids to elongated spermatids is known to be the main androgen-dependent step in spermatogenesis [ 35 36 37 ] .

  • If the Hsp70 in these aggregates retains the capacity to bind GR, this could account for the sequestration of nascent GR in these structures.

  • , reduced crop Impacts on commercial timber sales yields) Ozone impacts on carbon sequestration in commercial timber


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