Example sentences for: sequestered

How can you use “sequestered” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • They were present both in the ductal epithelium and in the periductal stroma, suggesting that the TGF-βs are synthesized by the epithelial cells, and possibly stromal cells, and are sequestered in the extracellular matrix.

  • SMAD4 (DPC4) is essential for this TGFβ 1 signaling and transcriptional activation process [ 16 ] . In epithelial cells, TGFβ 1 decreases c-myc, cdc2 and cyclin D1 expression, and it increases the expression of c-jun and c-fos [ 17 18 19 20 21 22 23 ] . Activation of the TGFβ 1 signal pathway in epithelial cells leads to an increased expression of the cell cycle inhibitors p21 WAF1and p15 Ink4band to a release of formerly sequestered p27 KIP [ 24 25 26 ] . It is assumed that the cooperative action of these cell cycle inhibitors results in the growth arrest mentioned above, although p15 Ink4bdoes not seem to be necessary in this regard.

  • The developmental stage distribution of circulating parasites, which also provides information on the sequestered parasites, was also evaluated in relation to plasma PfHRP2 levels in these patients.

  • In normal cells, p27 is sequestered and its activity gradually decreases as cells reach S phase, p27 preferentially binds cyclin D-cdk4, but lower levels of cdk4 (in TGF-β treated cells) allow p27 to be available for binding to the cyclin E-cdk2 and cyclin A-cdk2.

  • But none of the accounts mention whether the jury is sequestered yet.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast