Example sentences for: sequence-specific

How can you use “sequence-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As expected, the ribozyme sequence-specific primers produced a 430-bp PCR fragment only in cells infected with Ad-GFP/Rz-IGF2R, but not in cell infected with the control viral vector Ad-GFP.

  • The technique of RNAi, whereby the introduction of a sequence-specific double-stranded RNA leads to degradation of matching mRNAs [ 62 ] , has allowed the systematic surveying of thousands of C. elegans genes for phenotypes following transient gene knockout [ 63 64 65 ] . Such information is potentially transferable to understanding which genes have crucial roles in parasitic nematodes where high-throughput RNAi is not yet possible.

  • As the Y-box promoter element is crucial to the regulation of MHC class II gene expression, sequence-specific binding to this motif indicates a potential role for DEK in modulating normal and abnormal immune response.

  • To recap: by 1998—the year in which RNAi was reported—plant scientists had documented sequence-specific RNA degradation (PTGS), sequence-specific DNA methylation that triggered TGS, and RNA-directed DNA methylation.

  • RNA interference using sequence-specific siRNA can be successfully used to knock down profilin, a major actin-modulating protein of the eukaryotic cell.


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