Example sentences for: sequence-independent

How can you use “sequence-independent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Unlike other sequence-independent HMG-box proteins, which show ubiquitous tissue expression, we have previously shown that TOX has a highly regulated tissue and developmental expression profile.

  • Based on sequence alignment comparison with other previously characterized HMG-box proteins, we predict that the TOX HMG-box subfamily will likely fall into the sequence-independent category of HMG-box proteins.

  • Murine HMGB1 and yeast NHP6A bind DNA in a sequence-independent fashion.

  • Comparisons of human CD36 and mouse Cd36 genes indicate a high degree of sequence and structural similarity in both coding and regulatory regions, suggesting that the mechanism or mechanisms that underlie our findings are likely determined by sequence-independent, epigenetically distinct response patterns to the diabetic milieu that differ between these species.

  • Although there are few amino acid positions within the HMG-box motif that are conserved throughout the HMG-box protein superfamily, there are highly conserved residues within sequence-dependent and sequence-independent subgroups [ 21 ] . The vast majority of HMG-boxes have a tryptophan in helix 2, often as part of a GXXW motif (where X denotes any amino acid) [ 3 5 ] . Similarly, TOX has a tryptophan at this position, although as part of the less commonly found AXXW sequence.


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