Words similar to segregation
Example sentences for: segregation
How can you use “segregation” in a sentence? Here are some example sentences to help you improve your vocabulary:
In addition, we report that Rec12 and its active site tyrosine are required for proper equational chromosome segregation during MII.
, speciation without geographic segregation).
Examples include the polarized localization of oocyte mRNAs which is crucial for the establishment axis formation in the embryo [ 1 2 3 ] , the targeting of specific mRNAs to the synapses of nerve cells [ 4 5 ] , centrosomal segregation of mRNAs in the mollusk embryo which results in asymmetric inheritance [ 6 ] and the localization of β-actin mRNA to sites of active actin polymerization at the leading edge of motile fibroblasts [ 7 8 ] . In each of these cases, mRNA targeting is mediated by the cytoskeleton.
Abnormal chromosome segregation has been observed in mice lacking the Mad2 checkpoint protein [ 25 ] . The spindle checkpoint utilizes sensory proteins that detect kinetochore-microtubule tension and occupancy and transiently block anaphase until all of the chromosomes are properly attached to microtubules [ 16 26 27 ] . Although the mammalian spindle checkpoint appears to differ between mitosis and meiosis, the two meiotic divisions, and male and female germ cells [ 28 ] , anaphase subsequently follows stable kinetochore-microtubule attachments [ 17 29 ] in both vertebrate mitotic [ 30 ] and meiotic [ 31 ] cells.
Precocious separation of sister chromatids during MI [ 44 46 ] can also produce diploid meiotic products, 67% of which would be heterozygous for centromere markers (Figure 5D) [ 38 ] . However, the average heterozygosities in the rec12-117 and rec12-D15 mutants were significantly below this value, indicating that these mutants must have suffered some proportion of MII segregation errors.
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