Words similar to sdha
Example sentences for: sdha
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Mutations giving rise to Leigh syndrome have also been described in the flavoprotein subunit (Fp or SDHA) of the succinate dehydrogenase complex (SDH) [ 20, 21].
In fact, however, the high degree of sequence conservation over this entire region (Figure 7a) suggests that SDHA is fairly intolerant of mutations here.
The mutant version (C1684T, Arg554 → Trp; Figure 7a) of SDHA has a normal K m and K i (for malonate) but is much more sensitive to downregulation by oxaloacetate (OAA).