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Example sentences for: scop
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Whereas other resources are limited to what is present in PDB or SCOP, PAT provides additional domains from PDP, and genetic domains from Astral.
In the SCOP database, the α-subunit core domains have been classified together with several other domains, including the ligand-binding domain of the bacterial arginine repressor, the dimerization cofactor of the transcription factor HNF1 (DCOH), and a domain specific to the bacterial aspartyl-tRNA synthetases.
The 3D-Genomics database [ 12 ] uses SCOP domain PSSMs from 3D-PSSM [ 13 ] . Gene3D uses the CATH domain classification to annotate genes and genomes [ 14 ] .
The classical adenylyl cyclases, guanylyl cyclases and the GGDEF (diguanylate cyclase) domains share the catalytic palm domain with the family B DNA polymerases, reverse transcriptases, viral RNA dependent RNA polymerases and eukaryote-type primases [ 4 13 14 ] . The pathogenic adenylyl cyclases of several bacteria and the CyaA-like proteobacteria adenylyl cyclases are extremely divergent versions of the catalytic domain seen in the Pol-β family of nucleotidyl transferases [ 15 ] (also see SCOP database: http://scop.mrc-lmb.cam.ac.uk/scop/).
The use of SCOP classifications provides a hierarchical view of the data from a structure perspective.
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