Example sentences for: sclerosis

How can you use “sclerosis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Despite the significant progress in increasing our understanding of the immune mechanisms of multiple sclerosis (MS), in improving clinical classification and brain imaging, and in developing new treatments, the factors that determine the course of the disease are mostly unknown [1].

  • The automated system presented here applies robust image processing techniques to find important measures of degeneration in the aging spine, such as separation and angle between vertebrae, measurement of sclerosis, and orientation of vertebrae.

  • The technique has been applied to a broad range of other disorders, including multiple sclerosis [ 39 40 41 42 ] , Alzheimer disease [ 43 44 45 ] , type 1 diabetes [ 46 ] , type 2 diabetes [ 47 ] , asthma [ 48 ] , and systemic lupus erythematosus [ 49 ] . The use of such linkage-mapping strategies offers the advantage of model-independence, computational speed, and systematic identification of novel loci [ 39 ] .

  • 1 and 1q12, respectively [ 8 ] . These loci overlap with the genomic regions containing the genes for amyotrophic lateral sclerosis 5 (ALS5) and limb girdle muscular dystrophy 1B (LGMD1B), respectively [ 22 23 ] . We characterized these tropomodulin genomic loci for use in mutational analysis.

  • CMV, a herpes virus, causes chronic asymptomatic infections in immunocompetent individuals, termed latency [ 13 ] . However, in situations of immunocompromise, CMV is reactivated, which in many cases leads to organ failure and death [ 13 ] . Epidemiological reports indicate that chronic CMV infections in humans may play an important role in pathogenesis of vascular diseases such as atherosclerosis [ 14 ] and systemic sclerosis [ 11 12 ] . In addition, a recent report [ 15 ] revealed that SSc autoantibodies bind to CMV late protein UL94 and induce apoptosis in endothelial cells therefore implicating molecular mimicry as a potential mechanism accounting for the link between SSc and CMV.


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