Example sentences for: sclerosing

How can you use “sclerosing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Among the 175 cases, all contained non-invasive lesions, including ductal and lobular carcinoma in situ and sclerosing adenosis, and a few cases had invasive components.

  • Liver diseases associated with 1°SS include primary biliary cirrhosis (PBC)-autoimmune cholangitis [ 8 9 10 ] , autoimmune hepatitis [ 5 6 ] , viral hepatitis (B and C) [ 11 12 13 14 15 16 17 18 19 20 21 ] , sclerosing cholangitis [ 22 ] , and nodular regenerative hyperplasia [ 23 ] . In addition, chronic lymphocytic sialadenitis has been found in patients with different types of liver cirrhosis [ 16 17 18 19 20 21 22 23 24 ] .

  • Bacteria are found in the bile of the gallbladder and bile ducts [ 15 16 ] , the presence of which may have relevance to clinical diseases such as stone formation [ 19 20 21 ] , primary sclerosing cholangitis [ 22 ] , and cholestasis [ 23 24 ] . Direct exposure of sub-epithelial tissue to LPS from gram-negative bacteria causes release of cytokines by resident leukocytes and activation of macrophages [ 25 ] . The biliary fluid of patients with cholangitis has increased concentrations of the inflammatory cytokines TNF-α and IL-6 suggesting that bacterial infection leads to an increase in cytokines released into the bile [ 26 ] . Adding LPS to the bile of guinea pig gallbladders in vivo led to increased IL-1 concentration in the bile [ 27 ] . What role biliary epithelial cells play in the response to bacteria in bile is not known.


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