Words similar to sclc
Example sentences for: sclc
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It has also been shown that aspirin inhibited nitrosamine induced lung carcinogenesis [ 27 ] , and it reduced COX-2 enzyme levels in lung cancer cell lines [ 28 ] . Further support for a potential role of the COX-2 pathway in lung cancer development comes from several investigations that demonstrated COX-2 overexpression in human lung tumors, specifically NSCLC [ 29 30 31 32 ] and precursor lesions [ 33 ] . While COX-2 expression was generally shown to be increased in NSCLC and to a much lesser extent in SCLC, the role of COX-2 expression in latter tumor type is difficult to determine, due to the fact that the numbers of SCLC tumors examined in these studies was very small.
Tumor stage is the most significant prognostic parameter for 5-year survival, but even patients with non-small cell lung cancer (non-SCLC) in pathologic stage IA disease (a tumor of less than 3 cm diameter located in one lobe of the lung and more than 2 cm from the carina without visceral pleural involvement, atelectasis, or pneumonitis, and absence of metastatic spread to regional lymph nodes) have a 33% chance of recurrence within 5 years after complete surgical resection (lobectomy with mediastinal lymph node dissection) [ 2].
Finally, when we explored this risk association among histological subtypes, significant risk reductions were apparent in when controls were compared to patients with both NSCLC and SCLC.
86) and small cell lung cancer (SCLC) (adjusted OR = 0.32; 95% CI 0.16-0.
Our data are partly in contrast to these results, in that we observed the most marked reduction for SCLC, but also a significant decrease in risk for all NSCLC subtypes combined.
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